A PICO Analysis consists of . . .
P (patient, disease, population)
I (intervention)
C (comparative intervention)
O (outcome)
What is a systematic review? This article from the Annals of Internal Medicine describes various types and components.
"The conseientious, explicit and judicious use of current best evidence in making decisions about the care of the individual patient. It means integrating individual clinical expertise with the best available external clinical evidence from systematic research."
- David Sackett, M.D.